Floxepci

Uncategorized

Indications:

For the treatment of the following bacterial infections in patient of 18 years and older caused by bacteria susceptible to moxifloxacin

Description

Indications:

For the treatment of the following bacterial infections in patient of 18 years and older caused by bacteria susceptible to moxifloxacin

recommended for the initial treatment of these infections or when these have failed:

-Acute bacterial sinusitis .

-Acute exacerbations of chronic bronchitis.

-Community acquired pneumonia, except severe cases.

-Mild to moderate pelvic inflammatory disease .

-Complicated skin and skin structure infections .

Contraindications:

-Hypersensitivity to moxifloxacin , other quinolones

-pregnancy and lactation

-Patient below 18 years of age

-Patient with a history of tendon disease / Disorder related to quinolone treatment .

Both in preclinical investigations and in humans changes in cardiac electrophysiology have been observed following exposure to moxifloxacin , in the form of QT prolongation for reasons of drug safety , moxifloxacin is therefore contraindicated in patient with :

-Congenital or documented acquired QT prolongation

-Electrolyte disturbances , particularly in uncorrected hypokalaemia

-Clinically relevant bradycardia.

-Clinically relevant heart failure with reduced left-ventricular ejection fraction

-previous history of symptomatic arrhythmias

-Patient with impaired liver function

Overdose :

No specific countermeasures after accidental overdose are recommended in the event of over dose, symptomatic treatment should be implemented , ECG monitoring should be undertaken , because of the possibility of QT interval prolongation, concomitant administration of charcoal with a dose of 400mg oral moxifloxacin will reduce systemic , availability of the drugs products by more than 80% , the use of charcoal early during absorption may be useful to prevent excessive increase in the systemic exposure to moxifloxacin in cases of oral overdose.

Shelf Life :

3 years

Storage :

store at temperature not exceeding 30 celsius in a dry place

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